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SOURCE Decision Resources Group
Two New Therapies Will Match Progression-Free Survival Improvements Required By Surveyed U.S. Payers for Formulary Inclusion, According to a New Report from Decision Resources Group
BURLINGTON, Mass., June 5, 2014 /PRNewswire/ -- Decision Resources Group finds that in addition to an improvement in median overall survival (MOS), delayed disease progression is one of the greatest unmet needs in the first-line treatment of advanced ovarian cancer (CaO). MOS and disease progression are also key factors that shape surveyed U.S. and European oncologists' treatment decisions in this patient population. According to interviewed experts and survey data, substantial commercial opportunity exists for therapies that would improve MOS in first-line advanced CaO. Based on early-phase clinical data and the opinions of thought leaders interviewed the emerging therapies profiled by Decision Resources Group are not expected to offer significant improvements in overall survival, safety and tolerability, or delivery over currently used therapies. However, interviewed thought leaders anticipate that at least two emerging therapies; AstraZeneca's PARP inhibitor olaparib and Boehringer Ingelheim's angiogenesis inhibitor Vargatef will considerably prolong progression-free survival (PFS) in the first-line advanced CaO patients. The anticipated improvements in PFS offered by olaparib and Vargatef over the 2013 sales-leading regimen in this patient population, paclitaxel (Bristol-Myers Squibb's Taxol, generics) + carboplatin (Bristol-Myers Squibb's Paraplatin, generics), match the surveyed U.S. payers' PFS requirements for widespread inclusion on their managed care organizations' formularies.
Other key findings from the DecisionBase 2014 report entitled Ovarian Cancer (First-Line Advanced): Oncologists Are Eager for Therapies Extending Overall Survival:
Comments from Decision Resources Group Business Insights Analyst Natalia Reoutova:
About Decision Resources Group
Decision Resources Group offers best-in-class, high-value information and insights on critical issues within the healthcare industry. Clients rely on this analysis and data to make informed decisions. Find out more at www.DecisionResourcesGroup.com.
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